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Development of a Partial-Thickness Articular Cartilage Injury in an Ovine Model

Funding:

Orthopedic Research and Education Foundation

Principal Investigator:

Lee D. Kaplan, MD

Lab Website:

Dr. Kaplan's Research

Project Summary:

Partial thickness articular cartilage lesions (PARC) are commonly encountered during knee arthroscopy. The natural history of these lesions is not clearly delineated. The specific aims of this study are to develop a controlled, measurable PARC lesion in an animal model and evaluate the natural history of this pathological condition. The long-term objective is to utilize the resultant information from this project to develop and objectively analyze various treatment options. A PARC lesion will be made with a controlled, specifically designed instrument in a sheep (ovine) model with interval histologic and metabolic analyses up to one year.

 

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First published: 07/15/02 Last updated: 11/24/09 webmaster@ortho.wisc.edu
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