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Medications used in Spinal Injection Procedures

Not every medicine is used for all procedures. Medications given IV for sedation are optional for most procedures.

  1. Fentanyl is an opioid type pain medicine used during procedures for pain analgesia and sedation. Fentanyl decreases pain and may cause drowsiness. It is given through the IV. It acts quickly, with effects often felt in less than one minute. It is completely cleared from the body in 30 minutes to 1 hour. It is less likely to cause nausea than Demerol or morphine. The effects of fentanyl can be reversed with naloxone. If you have severe allergy to morphine, Demerol, Vicodin, Percocet, Dilaudid, or other pain medicines, please tell your healthcare provider prior to any procedures. Fentanyl is the active ingredient in Duragesic patches and Actiq lozenges.

  2. Versed (midazolam) is a benzodiazepine-type sedative medicine used during procedures for sedation. It also decreases anxiety. It is given through the IV. Midazolam may cause short-term amnesia and memory impairment, which may cause you to forget most of the procedure. The effect of midazolam can be felt in 1-5 minutes. Midazolam is completely cleared from the body in 30-80 minutes, but you should not drive for 24 hours after receiving midazolam because it can slow your reaction time. The effect of midazolam can be increased in patients who take opioid pain medicines. Midazolam should not be used in patients who are pregnant or who have acute angle closure glaucoma. The effects of midazolam can be reversed with flumazenil. If you have severe allergy to valium or other anti-anxiety or sleep medicines, please tell your healthcare provider prior to any procedures. If you have glaucoma, please check with your healthcare provider to see if this procedure is safe for you.

  3. Omnipaque 240 (iohexol) is nonionic iodinated contrast dye used during procedures to see needle position. It shows up on x-ray and CT scan for 30-60 minutes, and is completely cleared from the body in several hours. Usually you experience no symptoms from receiving Omnipaque. It contains iodine. If you are allergic to iodine, shellfish, or other contrast dye, please tell your healthcare provider prior to any procedures.

  4. Lidocaine (1%, preservative free) is a local anesthetic used for numbing during procedures. During spinal injection procedures, it is injected into the skin around the injection site and also into the area being injected. The effects are felt in less than 1 minute. The numbing effect lasts less than 2 hours. Even while the lidocaine is working, you still may be able to feel hot/cold and pressure, but sharp pain will be decreased. If you are allergic to lidocaine or any other local anesthetics, please tell your healthcare provider prior to any procedures.

  5. Bupivucaine (0.25%, 0.5%) is a local anesthetic used for numbing. During spinal injection procedures, it is used at the injection site. The effects are felt in 30-45 minutes and last 3-6 hours. You may experience loss of sensation and weakness in the affected area. If you are allergic to bupivucaine or any other local anesthetics, please tell your healthcare provider prior to any procedures.

  6. Celestone(betamethasone) is a steroid medicine used to decrease irritation and inflammation. During spinal injection procedures, it is used at the injection site. The effects are not felt for 2-3 days, and the effects may last from a few days to several months. Celestone may cause a temporary increase in pain for several days. This is called a steroid flare. The anti-inflammatory effect of Celestone may be increased in patients with hypothyroidism or cirrhosis. If you are diabetic, Celestone may temporarily increase your blood sugars. Other side effects from Celestone are very rare, as the medicine does not spread throughout the whole body. If you are allergic to Celestone or any other steroid medication, please tell your healthcare provider prior to any procedure.

  7. Depo-Medrol (methylprednisolone acetate) is a steroid medicine used to decrease irritation and inflammation. It is only used for interlaminar epidural steroid injections. It is used at the injection site. The effects are not felt for 2-3 days, and the effects may last from a few days to several months. Administration of Depo-Medrol may cause a temporary increase in pain for several days. The anti-inflammatory effect of Depo-Medrol may be increased in patients with hypothyroidism or cirrhosis. If you are diabetic, Depo-Medrol may temporarily increase your blood sugars. Other side effects from Depo-Medrol are very rare, as most of the medicine does not spread throughout the whole body. If you are allergic to Depo-Medrol or any other steroid medication, please tell your healthcare provider prior to any procedure.

More information about preparing for the procedure and what to expect before, during and after a spinal injection procedure.

 

UWIPP - First published: 02/14/03 Last updated: 11/07/09 webmaster@ortho.wisc.edu
Copyright © 2004 The Board of Regents of the University of Wisconsin System

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